Estron

• Hormonal product with luteolytic effect

Product Type:

• Hormones

Target Species:

• Horse, Pig, Cattle

Composition - 1 ml:

• Cloprostenolum sodium - 0.25 mg, chlorocresol, aqueous buffer - citric acid, sodium citrate, water.

Pharmaceutical form:

• Injection

Mode of action:

• Croscarmellose cloprostenol is a functional analogue of prostaglandin F 2 alpha and characterized by specific luteolytic effect. Extinction corpus lutea corresponding drop in progesterone levels, the manifestation of the onset of oestrus and ovulation in cows and mares. For sows induced by inducing labor.

Indication:

• biotech:

• synchronization and induction of estrus in heifers, cows and mares.
• Induction of parturition in sows.

• Scot:

• functional disorders of ovaries, postpartum and postservisní anestrus (silent heat, irregular and anovulatory cycle, persisting corpus luteum, luteal cyst).
• postpuerperální diseases of the uterus, endometritis, pyometra.
• interruption of normal and pathological pregnancy (in the first half of pregnancy).
• Combined therapy of follicular cysts (from day 10 after HCG or LHRH, after finding a positive ovarian response).

• mares:

• anestrus (silent heat, persistent diestrus, embryonic escheat, lactation anestrus, ending a pseudo). Interruption of normal and pathological pregnancy (in the first half of pregnancy).

Indications:

• Veterinary pharmaceutical preparation with luteolytic effect.

Storage:

• In a dry place at room temperature 10-25 ° C. Protect from light!

Shelf life:

• 1 year, the product must be used within 7 days after first opening.

packing:

• 5 x 2 ml, 10 x 2 ml, 20 x 2 mL, 5 x 10 ml

Route of administration:

• intramuscular

Dosage:

• Scot:

Oestrus synchronization:
• 2 ml of the product (0.50 mg of active substance) 2x spaced 10 days. The first dose is administered at any phase of the sexual cycle (in cows in the period from 40 to 60 days after birth). 11th day after the first application, a second dose, on the 14th day (72-76 hours after the second application) is carried out insemination (regardless of the external signs of heat) with the following reinseminací (day 15). Every application of medicine to induce synchronization in cattle must be preceded by examination of sexual organs. The prerequisite for the inclusion of animals in groups is a physiological condition of the genital organs, in heifers physical and sexual maturity.
Functional ovarian disorders:
• Administered 2 ml of the preparation, insemination after the first heat. If no oestrus, repeated administration of 2 ml of the 11th day after the initial application and subsequent insemination after 72-76 hours, possibly. reinseminací. In the therapy of follicular cysts are administered 2 ml of a one-off, first on day 10 after HCG or LHRH after finding a positive ovarian response. Rutting arriving third day after the administration of estron inj. ad us. vet.
Postpuerperální diseases of the uterus:
• Apply 2 ml of product, as necessary treatment can be supplemented intrauterine applications foams, event. lavage (preferably simultaneously with the application), the 11th day of repeated applications, the 14th day of insemination and day 15 reinseminace.
Interruption of pregnancy:
• 2 ml of the product (further treatment according to clinical status).

• Sow:

• A single dose of 0.7 ml (0.175 mg of active compound) is applied from 111 days of gestation.
• Most of induced births occur within 40 hours after application with the culmination of the 24th-35th hour.

• mares:

• A single application of 1 ml (0.25 mg of active substance).
• For cycling mares is applied at the time of 5 to 13 days after oestrus.
• The best time for the admission of the 4th to 6th day after application.

Contraindication:

• The product should not be used during pregnancy, particularly during the second half (with the exception of the indicated cases).

Interaction:

• They are not known

Side effects:

• For mares mild perspiration which disappears within 1-6 hours after application.

Special notes:

• The product must be used within 7 days after first opening. The product should not be handled by pregnant women.

Withdrawal periods:

• • Meat - 1 day
• • Milk - Zero days