BIOCAN DHPPi + L

• Vaccine against canine distemper, inf. laryngotracheitis, inf. hepatitis, parvovirosis, parainfluenza vivid and leptospirosis (L. icterohaemorrhagiae inact., L. canicola inact., L. grippotyphosa inact.) in dogs

Composition - 1 ml:

• Component DHPPi (freeze-dried):

Virus febris contagiosae canis min. 10^3,0 TCID₅₀, max.10^4,5 TCID₅₀
Virus laryngotracheitidis contagiosae canis min. 10^3,5 TCID₅₀, max.10^4,5TCID₅₀
 Parvovirus enteritidis canis min. 10^4,5 TCID₅₀, max.10^5,5TCID₅₀
Virus parainfluensis canis min. 10^3,0 TCID₅₀, max.10^4,2 TCID₅₀
Nutrimentum pro lyophilisatione ad 1 ml

• Component L (solution):

Leptospira icterohaemorrhagiae inact. min. 1 x 10^7,0, max. 1 x 10^9,0
Leptospira canicola inact. min. 1 x 10^7,0, max. 1 x 10^9,0
 Leptospira grippotyphosa inact. min. 1 x 10^7,0, max. 1 x 10^9,0
 Algeldrati suspensio. Nutrimentum ad cultivationem leptospirae

Drug form:

• Solution for injection

TARGET SPECIES ANIMALS:

• Dog

Immunological properties:

• After application of the vaccine to the animals body, antigens contained in the vaccine are identified as foreign particles and this is followed by activation of a large number of protection mechanisms in organism (macrophages, opsonins, interleukins, B-lymphocytes etc.), in result of which specific antibodies against antigen determinants contained in the vaccine are formed. These specific antibodies should prevent development of the disease in the event of infection. Immunity is starting after 14 days after first vaccination and firm immunity is developed after further 14 days after re-vaccination. Primovaccinated animals are revaccinated at an interval of 14 - 21 days. Annual revaccination is recommended to maintain immunity.

Indication:

• For the active immunization of dogs against distemper, infectious hepatitis, infectious laryngotracheitis, parvovirosis, parainfluenza and the most frequently occurred leptospira serovars in dogs at the age of 8 weeks and above.

Storage:

• Store in a dry and dark place at the temperature of 2 - 8 oC. Do not freeze!Do not use after the expiry date stated on the label. When diluted, the vaccine shall be used immediately.

Shelf life:

• 24 months

Package:

• 10 x 1 dose

Administration and dosage:

• 1 ml irrespective of animal's age, weight and breed. Method of administration - subcutaneous, preferably in zone behind the shoulder-blade at the age of 8 weeks and above, the re-vaccination shall be done within 14-21 day.

Interaction:

• The vaccine Biocan DHPPi + L can be used separately or simultaneously with other vaccines Biocan according to recommended vaccination scheme.

Contraindication:

• Total pyrexial disease

Adverse effects:

• Local reaction (like a pea in size) can be formed in the vaccine application spot that will disappear on its own accord within 3 weeks. Hypersensitivity can occur only rarely. Further possible vaccinations:
• Biocan M plus: vaccine against Microsporum canis for dogs of age 8 weeks and above
• Biocan B: vaccine against Lyme disease for dogs of age 12 weeks and above
• Biocan T: •vaccine against tetanus for dogs of age 12 weeks and above The vaccination scheme should be specified by the veterinarian in dependence on the infection situation and the level of the passive immunity obtained due to the colostric antibodies in the vaccinated individuals. The revaccination should be repeated every year in order to keep permanent immunity of the animals vaccinated.

Warning:

• Only clinically healthy animals in a good nutrition condition can be vaccinated. Possible anti-parasitic treatment should be carried out at least 10 days before the vaccination. The vaccinated animals should not be trained or exercised for one week after the vaccination. When diluted, the vaccine shall be used immediately.

Protection period:

• Not intended for food animals.